75 topics, 10 words, 500 iterations 

Anguish:

cried hands god face voice sake moment soul burst truth

Time/Setting:

night morning heard clock morrow bed early breakfast late waited

Finding a Body:

found dead man body blood knife lay stick carried sign

Losing Hope:

leave hope brought lost dear rest things true kindly wrong

Evidence:

important remarked case great evidence convinced shown show observed put

100 topics, 20 words, 1000 iterations

Smoking:

holmes pipe deal sat cigar tobacco short case smoke busy shining cigarette asked handed gas lit smoked smoking good clue

Facial Expressions:

face eyes turned looked lips sat pale expression fixed eager speak glass brow white horror staring turning emotion smile gleam

Praying:

cried god voice sake hope words soul heaven speak heavens jack frightened swear suggestion truth heart despair manner aid quick

Breaking In:

room door key entered table side locked safe open opened lock left inside furnished bureau doors drawer naturally carrying ascended

Night-Time:

night hour clock morning half past waiting ten morrow late twelve quarter eleven dressed vanished porter hurried sleep usual weary